维生素D缺乏与慢性心力衰竭

Vitamin D deficiency and chronic heart failure

慢性心力衰竭(CHF)目前仍是发病率、再住院率和死亡率均高的心血管疾病。尽管近年大量临床观察性和动物实验研究已证实低水平维生素D(vitamin D)与CHF的发病率和死亡率密切相关,但确切机制尚不确定。本文综述了近年维生素D与CHF的研究进展,以探讨维生素D在CHF发生发展讨程中的可能机制。

Chronic heart failure （CHF） is still a cardiovascular disease of high incidence rate, high readmission rate and high mortality.In recent years, a large number of clinical observational studies and basic animal studies have demonstrated that low vitamin D level is closely associated with the morbidity and mortality of CHF, but, the underlying mechanism between them remains unclear.The article reviewed the research progress of vitamin D and CHF in recent years so as to investigate the possible mechanism of vitamin D in the incidence and development of the disease.