弥漫硬化型甲状腺乳头状癌的研究进展

Research progress of diffuse sclerosing variant papillary thyroid carcinoma

弥漫硬化型甲状腺乳头状癌是甲状腺乳头状癌中的一种亚型，占甲状腺乳头状癌的0.7%-6.6%，其侵袭性强，复发、转移及持续带病率均比经典型甲状腺乳头状癌高。因此本病手术要求更严格、更彻底。由于弥漫硬化型甲状腺乳头状癌发病率低，许多临床医师对本病认识不足，临床诊治过程中易漏诊或误诊；因此本文将对弥漫硬化型甲状腺乳头状癌的流行病学、临床及病理特点等进行综述，以帮助临床医师对本病有进一步了解。

Diffuse sclerosing variant papillary thyroid carcinoma, one of the variants of papillary thyroid carcinoma, nearly account for 0.7% to 6.6% of papillary thyroid carcinoma. It is an aggressive tumor that shows higher rates of recurrence, metastasis and persistent disease compares to classic papillary thyroid carcinoma, thus diffuse sclerosing variant papillary thyroid carcinoma needs stricter and more exhaustive operation. Since the incidence of diffuse sclerosing variant papillary thyroid carcinoma is low, many physicians lack of understanding of the disease, it＇s often missed diagnosis or misdiagnosed. Consequently. In order to let physicians understand more about diffuse sclerosing variant papillary thyroid carcinoma, this paper will elaborate the epidemiology, clinic and pathology features of it.