中西医结合治疗小儿糖尿病临床研究

Clinical Study on the Treatment of Diabetes in Children with Integrated Traditional Chinese and Western Medicine

目的:观察中西医结合治疗小儿糖尿病的临床疗效。方法:72例小儿糖尿病患儿按照随机法将患儿分为观察组和对照组,每组各36例。对照组给予常规疗法,即常规胰岛素治疗法(使用剂量依据患儿自身情况而定)。观察组在对照组治疗基础上给予降糖方。比较两组患儿临床疗效、不良反应,治疗前后的血糖水平、糖化血糖蛋白水平、尿微量蛋白水平。结果:观察组患儿有效率为97.22%,对照组患儿有效率为86.11%,两组有效率比较,差异有统计学意义(P<0.05)。治疗后两组患儿空腹血糖、餐后2小时血糖、糖化血红蛋白、尿微量蛋白水平均降低,但观察组以上各指标均显著低于对照组(P<0.05)。观察组发生低血糖事件概率为2.88%,对照组为13.89%,两组比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗小儿糖尿病临床疗效显著。

Objective：To observe the clinical effect of integrated traditional Chinese and Western medicine in the treatment of children with diabetes. Methods：72 cases of children with diabetes were randomly divided into the observation group and the control group,each group of 36 cases. The control group was given conventional therapy,that is,conventional insulin therapy（ dose according to their own circumstances）. The observation group was treated with hypoglycemic prescription on the basis of the control group. The clinical efficacy,adverse reactions,blood glucose levels,the levels of glycosylated blood glucose and urine micro protein before and after treatment were compared between the two groups. Results：The effective rate of observation group was 97. 22%,and the control group was 86. 11%,the difference was statistically significant（ P〈0. 05）. After treatment,the fasting blood glucose,postprandial 2 hours blood glucose,glycosylated hemoglobin,urinary micro protein levels were reduced of the two groups,but the above indicators in the observation group were significantly lower than those in the control group（ P〈0. 05）. The incidence of hypoglycemia in the observation group was 2. 88%,the control group was 13. 89%,the difference was statistically significant（ P〈0. 05）. Conclusion：The combination of traditional Chinese and Western medicine treatment of children with diabetes clinical curative effect is remarkable.