善得定治疗重症急性胰腺炎32例疗效分析

Clinical analysis of 32 cases of serious acute pancreatitis(SAP) with Sandostatin

目的 观察善得定治疗重症急性胰腺炎的疗效。方法 32例重症急性胰腺炎随机分为对照组和治疗组各 16例。对照组给予禁食、持续鼻胃管减压 ,H2 受体拮抗剂 (西咪替丁或泰胃美 )抑制胃酸 ,解痉止痛等治疗。治疗组加用善得定 (第一天以每小时 2 5～ 5 0 μg速度持续静滴 ,而后每天 10 0 μg皮下注射 ,每日 3次 ,共 4～ 7天 )。结果 两组病人在疼痛缓解时间方面有显著性差异 (P <0 0 1) ,且对照组并发症明显增多。

Objective: To observe the effect of Sandostatin on the treatment for SAP Methods: Thirty two cases of SAP were randomly divided into the treatment group(16 cases) and the control group(16 cases) Fasting treatment and continuous nasogastric decompression were given in the control group,together with H 2 Cepter blocking drugs(Cimetidine or Tagamet) for inhibiting gastric acid, and antispastic and antibiotic for remitting ache The treatment group were treated with Sandostatin (first day, 25～50 μg/h, ivdrip, followed by 100 μg, H, q8h, 4～7 days) Results: There was significant difference between the two groups in the time of pain relief, and the complication decreased in the treatment group Conclusion: The results indicate that Sandostatin has very good effect on SAP