治疗教育在阿维A治疗儿童遗传性角化性疾病中的应用

Application of therapeutic education in the treatment of hereditary and keratinigztion disease in children through acitretin

目的:探讨治疗教育在阿维A治疗儿童遗传性角化性疾病中的应用价值。方法:选取2012年1月~2016年5月我所门诊收治的遗传性角化性疾病儿童68例为研究对象,采用随机数表法将其等分为观察组和对照组,均采用阿维A治疗,对照组给予常规健康教育及治疗,观察组在此基础上实施治疗教育,对比两组治疗效果,记录两组干预前后瘙痒、红斑、丘疹、苔藓化、鳞屑等症状与体征积分,采用皮损面积和严重程度指数(PASI)、皮肤病生活质量指数(DLQI)评价两组皮肤损伤程度及生活质量。结果:观察组治疗效果明显优于对照组(P<0.05);干预后观察组瘙痒、红斑、丘疹、苔藓化、鳞屑积分均较对照组低(P<0.05);干预后观察组PASI评分、DLQI评分均低于对照组(P<0.05)。结论:治疗教育可改善患儿症状与体征,提高患儿生活质量,值得临床推广。

Objective：To explore the application value of therapeutic education in the treatment of hereditary and keratinigztion disease in children through acitretin.Methods：A total of 68 children with hereditary and keratinigztion disease admitted in our hospital from January 2012 to May 2016 were selected as the research subjects.They were divided into observation group and control group by random number table method.All of them were treated with acitretin.The control group was given routine health education and treatment.On the basis of this,the observation group was treated with therapeutic education.The treatment effects of the two groups were compared.The symptoms and signs of the two groups with itching,erythema,papules,moss and scales were recorded.By using psoriasis area and severity index（ PASI） and dermatology life quality index（ DLQI）,the skin lesions and quality of life in the two groups were compared.Results：The treatment effect of observation group was better than that of the control group（ P〈0.05）.After treatment,the scores of itching,erythema,papules,moss and scales in the observation group were lower than those in the control group（ P〈0.05）.The scores of PASI and DLQI were lower in the observation group than in the control group（ P〈0.05）.Conclusion：Therapeutic education can improve the symptoms and signs of children as well as the quality of life of children.Therefore,it is worthy of clinical promotion.