羟磷灰石表面改性炭/炭复合材料牙种植体植入猪股骨内观察

Histological Observation of C/C Composite Dental Implants with Surface Modified by Hydroxyapatite Implanted into Femur of Pigs.

目的 :通过动物实验研究经羟磷灰石表面改性后的炭 /炭复合牙种植材料与骨组织结合的界面。方法 :将10只仔猪随机分为实验组和对照组 ,阴性对照材料采用钛芯羟磷灰石涂层种植体 ,阳性对照材料采用普通碳钢 ,将实验材料和对照材料分别植入猪的股骨中 ,3个月后处死动物观察材料与骨组织的结合界面。结果 :在实验组的 5例中有 2例种植体与骨组织形成骨性结合界面 ,另外 3例种植体与骨组织形成纤维骨性结合界面。阴性对照组中4例种植体均与骨组织形成骨性结合界面。阳性对照材料周围被极度疏松的骨组织所包围 ,碳钢与疏松的骨组织之间存在间隙。结论 :这种经羟磷灰石改性的炭

Objective:To study the interface between the bone and C/C composite dental implants with the surface modified by hydroxyapatite through animal experiment.Methods:Ten young pigs were divided into experimental group and control group randomly.The pigs of control group were implanted hydroxyapatite-coated titanium implants and normal steel respectively to observe the negative reaction and positive reaction. Experimental materials and control materials were implanted into femur of pigs.The pigs were killed to observe the interface between the materials and the bone after 3 months.Results:In the experimental group, osseo-integrated interface was found in 2 pigs of the total 5 pigs, and fibro-osseo- integrated interface was found in other 3 pigs.In the control group,osseo-integrated interface was found in the 4 pigs in which the hydroxyapatite-coated titanium implants were implanted,but the bone around the normal steel is much porous.There is a gap between the porous bone and normal steel.Conclusions:Two kinds of interfaces ( osseo-integrated interface and fibro-osseo- integrated interface ) are present between the bone and this kind of modified layer of C/C composite dental implants.