原发性肝癌患者术后早期复发转移的影响因素分析

Analysis of the status of postoperative recurrence and metastasis of hepatocellular carcinoma and its influencing factors

目的探讨影响原发性肝癌患者术后早期复发转移的危险因素,为延长患者的生存时间及临床治疗提供依据。方法回顾性分析200例原发性肝癌患者的临床资料,对术后复发转移的危险因素进行Logistic回归分析。结果 200例患者中,120例(60%)出现了术后复发转移。术前肝硬化、包膜不完整、多结节融合、有门静脉肉眼癌栓、肝门总阻断时间﹥15 min是原发性肝癌患者术后复发转移的危险因素。结论原发性肝癌患者术后早期复发转移率较高,对于术前有肝硬化、包膜不完整、多结节融合、有门静脉肉眼癌栓及肝门总阻断时间较长的患者,需加强术后复诊和康复治疗。

Objective To explore the risk factors of postoperative recurrence and metastasis of patients with hepato-cellular carcinoma （HCC）, and to provide references for improving survival and clinical treatment of patients. Method A retrospective analysis was conducted, in which 200 patients with primary HCC were analyzed for factors influencing the postoperative recurrence and metastasis by Logistic regression. Result Of the 200 patients, 120 （60%） had recur-rence and metastasis after surgery. The presence of prior cirrhosis, incomplete membrane, confluent multinodular HCC, visible portal vein tumor thrombosis and time of portal vein obstruction〉15 min were risk factors of the occurrence of postoperative recurrence and metastasis. Conclusion High rates of early recurrence and metastasis are observed in hepa-tocellular carcinoma patients, postoperative care should be strengthened for those patients with prior liver cirrhosis, in-complete membrane, visible portal vein thrombosis and with a prolonged time of portal vein obstructions.