肝动脉化疗栓塞联合CT引导射频消融治疗肝尾状叶原发性肝癌

Transcatheter hepatic arterial chemoembolization combined with CT guided radiofrequency ablation for treatment of primary liver cancer in caudate lobe

目的探讨经肝动脉化疗栓塞(TACE)联合CT引导射频消融(RFA)治疗肝尾状叶原发性肝癌的疗效及安全性。方法回顾性分析肝尾状叶原发性肝癌患者16例,均先行TACE治疗,再行CT引导下RFA治疗,随访患者的手术并发症、无瘤生存时间及总生存时间。结果 15例患者实现完全消融,完全消融率为93.75%(15/16)。完全消融患者的无瘤生存时间为19.35个月。16例患者的总生存时间为44.62个月,1、3、5年的总生存率分别为88.23%、66.65%及33.18%。结论 TACE联合RFA治疗肝尾状叶原发性肝癌安全、有效。

Objective To evaluate the efficacy and safety of transcatheter hepatic arterial chemoembolization （TACE） combined with CT guided radiofrequency ablation （RFA） for primary liver cancer in the caudate lobe. Methods Sixteen patients with primary liver cancer in the caudate lobe were treated with combination therapy of TACE and RFA. Complet ablation rate, overall and recurrence-free survival, and complications were evaluated. Results A total of 15 cases achieved complet ablation, complet ablation rate was 93.75% （15/16）. Recurrence-free survival time was 19.35 months, overall survival time was 44.62 months. Overall survival rates were 88.23%, 66.65% and 33.18% at 1, 3, 5 years after therapy, respectively. Conclusion TACE combined with RFA is a safe and useful therapeutic option for treatment of primary liver cancer in the caudate lobe.