急性早幼粒细胞白血病治疗的研究进展

Recent advances in management of acute promyelocytic leukemia

急性早幼粒细胞白血病（APL）为急性髓细胞白血病的特殊亚型，其主要临床特征为严重的凝血功能障碍、出血倾向，并且患者早期病死率高。随着对APL研究的不断深入，该疾病成为目前治愈率最高的白血病。为了更好地指导APL的临床治疗，进一步提高APL患者的生存质量，笔者拟就APL治疗研究进展进行综述。

Acute promyelocytic leukemia （APL） is a special subtype of acute myeloid leukemia. Its main clinical features are severe coagulopathy, bleeding tendency and high early mortality. With the continual advances in APL research, APL has become a kind of curable leukemia with the highest cure rate at present. In order to further guide the therapy of APL and improve the quality of life of patients with APL, this article reviews current advances of treatment of APL.