有机磷中毒患者接受不同阿托品给药方式的临床效果分析

Analysis on the Clinical Effect of Different Methods of Administration of Atropine in Patients with Organophosphate Poisoning

目的:讨论有机磷中毒患者采用不同阿托品给药方式的临床治疗效果。方法:以我院在2015年1月至2016年3月收治的100例有机磷中毒患者作为研究对象,随机将其分为对照组和观察组,每组各50例,对照组患者使用间静脉推注方式给药治疗,观察组患者使用持续性静脉滴注方式给药治疗。比较两组患者临床治愈率以及使用阿托品剂量、住院时间和阿托品化时间。结果:观察组患者治愈率为96%,对照组患者治愈率为70%,两组之间差异有统计学意义(P<0.05);观察组阿托品化时间、使用阿托品剂量以及患者住院时间均优于对照组,两组之间差异有统计学意义(P<0.05)。结论:有机磷中毒患者在临床治疗中,采用持续性静脉滴注阿托品的给药方式,能够有效减少阿托品化时间,提高患者治愈率,同时还能减少阿托品使用剂量以及患者住院时间。

Objective： To discuss the clinical effect of using atropine in patients with organophosphate poisoning. Methods： In our hospital patients as the research object in 100 cases of organophosphorus in January 2015-2016 year in March, and were randomly divided into control group and observation group. The control group was treated with intravenous injection between the way for the medicine, the observation group was treated with continuous intravenous infusion of the way to medicine. The cure rates of the two groups were compared, and the length of hospital stay and the time of atropine. Results： The cure rate of observation group was 96%, and the cure rate was 70% in the control group, there were significant differences between the two groups （ P 〈 0. 05 ）, have statistical significance. To observe the dose of atropine and atropine used time and hospitalization time of patients were better than the control group, there is significant difference between the two groups was statistically significant（P 〈0. 05）. Conclusion： The organic phosphorus of patients in clinical treatment, the use of atropine for continuous intravenous administration of atropine, can effectively reduce the time and improve the cure rate of patients, but also reduce the dosage of atropine and hospitalization time of patients, is worthy of promotion in clinical use.