107例食管癌、胃癌病例分析

The Analysis of 107 Cases with Esophageal Cancer and Gastric Cancer

目的通过研究食管癌和胃癌的发病特点,提高基层医院食管癌和胃癌的诊断水平。方法回顾性分析2012年2月至2013年8月成都市新都区中医医院胃镜联合病理活检确诊的107例食管癌和胃癌患者资料,比较其性别、年龄分布及肿瘤发病部位,并统计胃癌患者幽门螺杆菌(helicobacter pylori,Hp)感染情况。结果男、女患者所占百分率分别为77.57%和22.43%。食管癌、胃癌患者男、女百分比分别为95.83%、4.17%和62.71%、37.29%,两组性别分布差异有统计学意义(P<0.001)。食管癌和胃癌患者在<60岁、≥60岁所占比例分别为43.75%、56.25%和22.03%、77.97%,差异有统计学意义(P=0.016)。肿瘤部位在食管上段、中段、下段所占比例分别为10.42%、60.41%、29.17%。胃癌患者肿瘤部位在贲门、胃体、胃窦、胃角所占比例分别为23.73%、25.42%、38.98%、11.86%,其Hp检测阳性率为77.97%。结论男性食管癌、胃癌发病率明显高于女性,大于60岁为高发人群,食管癌和胃癌的最常见发病部位分别为食管中段和胃窦部。Hp感染和胃癌有关。胃镜联合病理活检是诊断食管癌和胃癌的最主要手段。

Objective To study the clinical features of esophageal cancer and gastric cancer and improve the diagnostic level of the primary hospital for those diseases.Methods The data of 107 patients who were diagnosed with esophageal cancer and gastric cancer via the endoscopy and the pathological biopsy in Xindu Hospital of Traditional Chinese Medicine between February of 2012 and August of 2013 were analyzed retrospectively.The patients′gender,age,and the lesion location were compared,and the gastric cancer patients infected by Helicobacter pylori（Hp）were analyzed statistically.Results The male and female patients accounted for 77.57%and 22.43% respectively.The percentages of the male and female were 95.83% and 4.17% among the patients with esophageal cancer,while the percentages were 62.71% and 37.29% respectively among the patients with gastric cancer,which showed significant differences in gender between the two groups（P〈0.001）.The patients with esophageal cancer who were no more than 60 years old or no less than 60 years old accounted for 43.75% and56.25% respectively,while those with gastric cancer who were no more than 60 years old or no less than 60 years old accounted for 22.03% and 77.97% respectively,which demonstrated significant differences in age between the two groups（P=0.016）.The gastric cancer patients with the tumor in gastric cardia,gastric body,gastric antrum,gastric angle proportion accounted for 23.73% 25.42%,38.98%,and 11.86% respectively,and the positive rate of Hp was 77.97%.Conclusion The incidence rate of esophageal cancer and gastric cancer in the male patients is significantly higher than in the female patients.People with over 60 years old are the high risk population,and the male patients with esophageal cancer are the majority.The most common location of esophageal cancer and gastric cancer are in the mid esophagus and the gastric antrum.Hp infection is highly correlated with gastric cancer.Gastroscopy combined with pathological biopsy is the most important method for diagnosing esophageal cancer and gastric cancer.