外科手术与血管栓塞治疗伴动眼神经麻痹性后交通动脉瘤疗效对比观察

Clinical Effect Comparison of Surgical Operation and Embolization Therapy for Patients with Oculomotor Nerve Paralysis and Posterior Communicating Aneurysms

目的探讨外科手术与血管栓塞治疗伴动眼神经麻痹性后交通动脉瘤疗效对比观察。方法将该院2014年1月—2016年6月收治的116例伴动眼神经麻痹性后交通动脉瘤患者随机分为两组。对照组58例采用外科手术治疗,而试验组58例采用血管栓塞治疗,比较两组患者手术住院、动眼神经恢复及并发症的差异。结果试验组患者手术耗时、术中出血量、住院时间及住院费用均低于对照组,比较差异有统计学意义(P<0.05);试验组患者动眼神经恢复率为93.1%稍高于对照组91.4%,比较差异无统计学意义(P>0.05);试验组患者脑水肿、脑血管痉挛发生率分别为6.9%、12.1%显著低于对照组22.4%、32.8%,比较差异有统计学意义(P<0.05)。结论血管栓塞治疗较外科手术治疗伴动眼神经麻痹性后交通动脉瘤疗效显著,其手术耗时短、出血少、费用短、并发症也较少,动眼神经恢复也较好,值得临床选择。

Objective To compare the clinical effect of surgical operation and embolization therapy for patients with oculomotor nerve paralysis and posterior communicating aneurysms. Methods 116 patients with oculomotor nerve paralysis and posterior communicating aneurysms from January 2014 to June 2016 in our hospital were selected. The subjects were randomly divided into two groups,58 cases each group. The control group adopted the surgical operation; the test group adopted the embolization therapy. The operation condition,recovery of oculomotor nerve and complications for two groups were compared. Results The operation time,intraoperative bleeding volume,hospitalization time and hospitalization cost for test group was better than that of control group,the difference was statistically significant（P 〈0.05）; the recovery rate of oculomotor nerve for test group（93.1%） was slightly higher than that of control group（91.4%）,the difference was statistically significant（P 〉0.05）; the incidence rate of cerebral edema and cerebral angiospasm for test group was 6.9% and 12.1%; the rate for control group was 22.4% and 32.8%,the difference was statistically significant（P〈0.05）.Conclusion Compared with the surgical operation,the embolization therapy has a bettter effect for patients with oculomotor nerve paralysis and posterior communicating aneurysms. It is featured as shorter operation time,lower bleeding volume,lower hospitalization costs,fewer complications and better recovery of oculomotornerve. It shall be recommended in clinical practice.