Effect of Instant Asparagus Powder on Sleeping Disorder

速溶芦笋粉改善睡眠作用研究（英文）

[Objective] This study was to evaluate the efficacy of instant asparagus powder, a functional food made of asparagus, for improving sleep quality. [Method] A total of 60 volunteers were selected, and each of them consumed two bags of instant asparagus powder （24 g） once a day for 60 consecutive days. Then, the sleep quality of the volunteers was evaluated. At the same time, the safety indices and insomnia-related endocrine indices were determined. [Result] Instant asparagus powder significantly increased the sleep time of sleep disorders from 5.1 to 6.1 h, shortened the time to fall asleep from 50.4 to 25.3 rain, and reduced the time to fall asleep after being awake from 46.5 h to 19.5 h. The differences before and af- ter the consumption of instant asparagus powder were significant （P〈0.05）. The sat- isfaction of sleep quality was high. Instant asparagus powder had good safety with- out liver and kidney function influence. Instant asparagus powder could reduce the levels of cortisol and norepinepthrine and increase the levels of serotonin and dopamine. [Conclusion] Instant asparagus powder could improve the quality of sleep, characterized by safety and effectiveness. The sleep quality-improving effect of in- stant asparagus powder might be related to the regulation of HPA axis or the regu- lation of serotonin secretion.

[目的]评价以芦笋为原料开发的功能食品速溶芦笋粉改善睡眠功效。[方法]通过60名志愿者试食实验,每日食用一次,一次两袋(24 g),连续食用60 d,进行睡眠状况评估,同时测定安全性指标及失眠相关内分泌指标,观察速溶芦笋粉对人体睡眠障碍的改善作用。[结果]速溶芦笋粉可明显增加有失眠困扰测评者有效睡眠时间,由5.1 h延长至6.1 h;缩短入睡时间,由50.4 min缩短到25.3 min;醒后再入睡时间明显减少,平均时间由46.5 h减少至19.5 h,食用前后差异显著(P<0.05),测评者对睡眠质量改善满意度较高。食用后无肝肾功能影响,具有较好的安全性。速溶芦笋粉可以降低皮质醇、去甲肾上腺素水平,提高5-羟色胺、多巴胺水平。[结论]人体试食试验表明,速溶芦笋粉有改善睡眠质量作用,安全有效,其改善睡眠作用可能与调节HPA轴或调节5-羟色胺分泌相关。