广东省珠海地区儿童慢性咳嗽病因构成分析

Analysis on etiology of children with chronic cough in Zhuhai region of Guangdong province

目的探讨珠海地区儿童慢性咳嗽的病因构成,为临床诊断治疗提供参考。方法采用《中国儿童慢性咳嗽诊断与治疗指南(2013年修订)》提供的原则和思路,对150例慢性咳嗽患儿的临床资料进行回顾性分析,总结其病因特点。结果 150例慢性咳嗽的患儿中,咳嗽变异性哮喘(CVA)52例,上气道咳嗽综合征(UACS)50例,呼吸道感染与感染后咳嗽(PIC)29例,胃食管反流性咳嗽(GERC)3例,气道异物或畸形2例,非哮喘性嗜酸性粒细胞性支气管炎(NAEB)1例,CVA+UACS 11例,PIC+UACS 2例。结论儿童慢性咳嗽病因较为复杂,珠海地区儿童慢性咳嗽病因构成比前3位是咳嗽变异性哮喘、上气道咳嗽综合征、呼吸道感染与感染后咳嗽,不同年龄组患儿病因有所不同;结合病史资料、临床表现、实验室检查明确病因,针对病因治疗,提高诊治水平。

Objective To explore the etiology of children with chronic cough in Zhuhai region,and provide reference for clinical diagnosis and treatment. Methods Based on the guideline for diagnosis and treatment of Chinese children with chronic cough in 2013,the clinical data of 150 children with chronic cough was analyzed retrospectively,the etiological characteristics were summaried. Results This study found 52 children with cough variant asthma（ CVA）,50 children with upper airway cough syndrome（ UACS）,29 children with post-infection cough（ PIC）,3 children with gastroesophageal reflux cough（ GERC）,2 children with foreign body or malformation in airway,one child with non-asthma eosinophilic bronchitis（ NAEB）,11 children with both CVA and UACS,2 children with both PIC and UACS.Conclusion The causes of chronic cough in children are complex,the top three important causes of children with chronic cough in Zhuhai region are CVA,UACS,respiratory tract infection and PIC. The children in different age groups have different causes. The diagnostic and therapeutic level can be improved based on medical history,clinical features,and laboratory examination.