胎膜早破合并早产院内感染的临床因素分析

Clinical analysis of hospital infection in premature rupture of membranes combined with premature

目的探讨胎膜早破合并早产院内感染临床相关危险因素。方法选取2013年2月~2016年2月我院收治86例胎膜早破合早产患者为研究对象,根据患者是否合并有院内感染分为感染组和非感染组,采用Pearson单因素和Logistic多因素回归分析两组患者一般临床资料,探析胎膜早破合并早产发生院内感染临床危险因素。结果 86例胎膜早破合并早产患者合并院内感染12例,占13.95%。单因素分析得出,感染组患者免疫功能低下、侵入性操作、破膜时间长、剖宫产、抗生素未广泛使用、住院时间长占有比例显著高于非感染组患者,差异有统计学意义(P<0.05)。多因素分析指出,免疫功能低下、侵入性操作、破膜时间长、剖宫产、未广泛使用抗生素及住院时间延长均为影响胎膜早破合并早产院内感染危险因素。结论胎膜早破合并早产院内感染危险因素较多,临床中应针对性进行预防和控制,以降低胎膜早破合并早产患者院内感染发生率。

Objective To discuss the clinical risk factors of hospital infection in premature rupture of membranes combined with premature. Methods 86 cases with premature rupture of membranes combined with premature in hospital from Feb. 2013 to Feb. 2016 were selected as studying objects, and all cased were divided into infection group and non-infection group according to whether or no hospital infection. General clinical data were analyzed by Pearson single factor and Logistic regression analysis, and the clinical risk factors of hospital infection in premature rupture of membranes combined with premature were analyzed. Results 12 cases with premature rupture of membranes combined with premature in 86 cases were with hospital infection, accounting for 13.95%. Single factor analysis showed that： Low immune function, invasive operation, long rupture time, cesarean section, no widely antibiotics use and long hospital stay rates of infection group were higher than those of non- infection group （ P 〈 0.05 ）. Multiple factor analysis showed that： Low immune function, invasive operation, long rupture time, cesarean section, no widely antibiotics use and long hospital stay were risk factors of hospital infection in premature rupture of membranes combined with premature. Conclusion The risk factors of hospital infection in premature rupture of membranes combined with premature are many. Prevention and control measures should be carried out in order to reduce the incidence of hospital infection.