胺碘酮联合美托洛尔静脉注射治疗快速心律失常效果观察

The Clinical Effect of Amiodarone Combined with Metoprolol Intravenous Injection in Treatment of Tachyarrhythmia

目的:探讨胺碘酮联合美托洛尔静脉注射治疗快速心律失常的临床效果。方法:选择122例快速心律失常患者,随机分为观察组和对照组。对照组给予胺碘酮治疗,观察组给予胺碘酮和美托洛尔联合治疗。测定两组患者治疗前后血压及心率,评定治疗效果。结果:治疗前观察组和对照组血压(收缩压、舒张压)及心率比较差异均无统计学意义(P>0.05);治疗后观察组血压(收缩压、舒张压)及心率均低于对照组,差异均有统计学意义(P<0.05)。观察组窦性心律转复发生率高于对照组,观察组治疗后有效率高于对照组,差异均有统计学意义(P<0.05)。结论:胺碘酮联合美托洛尔静脉注射治疗快速心律失常效果显著,窦性心律转复发生率高,值得借鉴。

Objective： To explore the clinical effect of Amiodarone combined with Metoprolol intravenous injection in treatment of tachyarrhythmia. Method： 122 patients with arrhythmia were randomly divided into observation group and control group.The control group was treated with Amiodaronet, the observation group was treated with Amiodarone and Metoprolol.The blood pressure and heart rate were measured before and after treatment in two groups, The clinical effect was evaluated. Result： The blood pressure （systolic blood pressure and diastolic blood pressure） and heart rate in the observation group before treatment respectively compared with those in the control group before treatment, the differences were not statistically significant（P〉0.05）.The blood pressure （systolic blood pressure and diastolic blood pressure） and heart rate in the observation group after treatment were respectively lower than those in the control group after treatment, the differences were statistically significant （P〈0.05）.The rate of sinus rhythm conversion in the observation group was higher than that in the control group, and the effective rate of the observation group was higher than that of the control group, the differences were statistically significant（P〈0.05）.Conclusion： Amiodarone combined with Metoprolol injection has significant effect for arrhythmia, which has high incidence rate of sinus rhythm cardioversion, the therapy is worthy of reference.