麻子仁丸治疗小儿功能性慢性便秘临床观察

Clinical observation on the treatment for children with chronic functional constipation by Cannabis pill

目的观察麻子仁丸治疗小儿功能性慢性便秘肠胃积热证的临床疗效。方法将2014年7月至12月在北京市昌平区中医医院确诊的100例慢性便秘患儿随机分为观察组和对照组各50例。观察组给予麻子仁丸加减治疗,对照组给予枯草杆菌肠球菌二联活菌多维颗粒治疗,两组均治疗1个月,观察两组临床疗效及主要症状体征疗效。结果观察组总有效率为96.0%(48/50),高于对照组78.0%(39/50),差异有统计学意义(P<0.05)。观察组主要临床症状体征中大便干、排便周期延长、口干口臭、面红身热和心烦不安总有效率显著高于对照组,差异有统计学意义(P<0.05)。两组腹胀痛、排便困难改善比较差异无统计学意义(P>0.05)。结论麻子仁丸治疗小儿慢性便秘属肠胃积热证疗效显著。

Objective To observe the clinical effect of Cannabis pill on gastrointestinal heat syndrome in children with chronic functional constipation. Methods A total of 100 children with chronic constipation, who were diagnozed in TCM Hospital of Changping District in Beijing from Jut. 2014 to Dec. 2014, were randomly divided into two groups： the observation group and the control group, 50 cases in each. The ob- servation group was treated with Cannabis pill（modified） and the control group received live combined gran- ules of Bacillus subtilis and Enterococcus faecium. The treatment lasted one month for both groups. Ob- serve the clinical effect of the two groups as well as the effect on the main symptoms and signs. Results The total effective rate of the observation group was 96.0% （48/50）, higher than that of the control group was （78.0% ,39/50） ,and the difference was statistically significant（P〈0.05）. The effective rate of observation group was significantly higher than that of the control group on such symptoms and as dry feces, lengthe- ning interval of bowel movement, dry mouth and bad breath, flushing, fever and being upset, and there was statistical difference （P〈0.05）. There was no statistical difference between the two groups on the improve- ment of abdominal distention and pain and difficult defecation（P〈0.05）. Conclusion Cannabis pill has sig- nificant effect on chronic constipation in children（gastrointestinal heat syndrome）.