孕妇宫颈分泌物解脲支原体和沙眼衣原体检测的临床意义

The detection of ureaplasma urealyticum and chlamydia trachomatis in cervi-cal secretion of pregnant women and its clinical significance.

目的探讨孕妇宫内解脲支原体、沙眼衣原体感染与胎膜早破、产褥感染及新生儿并发症之间的关系。方法采用定性PCR技术对随机选取的108例胎膜早破和100例同期正常产妇的宫颈分泌物中解脲支原体(UU)和沙眼衣原体(CT)进行检测,并结合临床资料进行分析。结果胎膜早破组UU或CT的阳性率为72.22%,其中UU阳性率60.19%,CT阳性率16.67%,两者混合感染率4.64%,均明显高于对照组;胎膜早破组的难产率显著升高;在UU或CT阳性者中,产褥病率及新生儿并发症发生率也明显高于阴性者。结论孕妇宫内UU、CT感染与胎膜早破密切相关,其检测对临床预防胎膜早破,减少产褥病及新生儿并发症的发生率具有重要的临床应用价值。

Objective To probe into the relationship between intrauterine infection with ureaplasma urealyticum(UU),chlamydia trachomatis(CT)and premature rupture of membrane(PROM),puerperalism and neonatal complica tions.Methods Polymerase chain reaction technique was used to detect UU and CT in cervical secretion of preg-nant women with PROM and the control,and the results were analyzed in combination with clinical data.Re sults The total infectious rate of UU or CT in the PROM group was72.22%,with that of UU60.19%and CT16.67%,and the mixed infectious rate of the two was4.64%,All the infectious rates in the PROM group were higher than those in the control group.The rate of difficult labour in PROM markedly increased,the incidence of puerperalism and neonatal complications in the positive UU or CT group were significantly higher than those of the negative group as well.Conclusions In-trauterine infection with UU and CT in pregnant women is closely related to PROM,and the detection of UU and CT is of clinical value in preventing PROM and reduce puerperalism and neonatal complications