分析比较静脉推注胺碘酮与西地兰治疗快速阵发性房颤的效果

Clinical efficacy of Intravenous injection of amiodarone and cedilanid in the treatment of rapid atrial fibrillation

目的探索研究静脉推注胺碘酮与西地兰治疗快速阵发性房颤的临床效果。方法选取我院2013年12月~2016年12月收治的60例快速阵发性房颤患者,随机分为观察组和对照组,每组各30例。对照组采用西地兰治疗,观察组采用胺碘酮治疗。结果观察组治疗总有效率明显高于对照组(P<0.05)。两组患者组内对比用药后心率较治疗前明显降低、血压较治疗前降低(P<0.05);观察组患者转复窦律时间明显少于对照组患者(P<0.05)。两组患者不良反应发生率差异不明显(P>0.05)。结论采用胺碘酮治疗快速阵发性房颤效果良好,转复窦律时间快,患者心率、血压改善情况良好,不良反应少,值得在临床中推广应用。

Objective To discuss the clinical efficacy of intravenous injection of amiodarone and cedilanid in the treatment of rapid atrial fibrillation. Methods 60 cases with rapid paroxysmal atrial fibrillation in our hospital from December 2013 to December 2016 were selected as objects.All cases were randomly divided into observation group and control group with 30 cases in each group.The control group treated with cediland,and the observation group was treated with amiodarone. Results The total effective rate of the observation group was significantly higher than that of the control group（P 〈 0.05）.After treatment,heart rates of two groups were significantly lower than before treatment,and the blood pressure was lower than before treatment（P 〈 0.05）.After treatment,the heart rate of the observation group was lower than that of the control group,and the blood pressure was lower than that of the control group（P 〈 0.05）;Converting to sinus rhythm time of the observation group was significantly shoreter than that of the control group（P 〈 0.05）.The adverse reaction rates of two groups were not significantly different（P〉 0.05）. Conclusion Amiodarone in the treatment of rapid atrial fibrillation shows good clinical efficacy,shorter converting to sinus rhythm time,and can reduce HR and BP,with less adverse reactions,worthy of clinical promotion.