量子点荧光印迹传感器的计算机模拟设计、制备及检测河水中4-硝基苯酚的应用

Computer Simulation Design,Preparation and Application of Fluorescence Sensors Based on Quantum Dots for Selective Detection of 4-Nitrophenol in River Water

将量子点的荧光特性、表面分子印迹技术与计算机模拟技术相结合,分别以碲化镉、4-硝基苯酚、3-氨丙基三乙氧基硅烷和正硅酸四乙酯作为量子点、模板分子、功能单体和交联剂,制得具有荧光特性的分子印迹聚合物.对其结构、形貌、荧光性能和选择性进行了表征,结果表明,该聚合物对4-硝基苯酚具有良好的选择性和灵敏度,线性范围为1.0~80 nmol/m L,检出限为0.05 nmol/m L.将制备的量子点荧光印迹聚合物作为传感器,应用于河水中4-硝基苯酚的测定,加标回收率为98.6%~101.2%,相对标准偏差最高为1.37%.

To fabricate a fluorescent sensor, molecularly imprinted polymers （MIPs） with 4-nitrophenol （4-NP） as the template molecule were prepared on the surface of as-synthesized hybrid SiO2-coated CdTe （HS-QD） by combining molecular dynamics simulations with surface imprinting technique. The sensor was characterized by several methods in terms of structure, morphology, fluorescence properties and selectivity. The sensor has a higher sensitivity as well as good selectivity. The relative fluorescence intensity of HS-QD@ MIP decreased linearly with the increasing concentration of 4-NP in the range of 1.0--80 nmol/mL with a detection limit of 0. 05 nmol/mL. The method was also employed to detect 4-NP in the river water samples with satisfactory recoveries of 98.6%-101.2%, and the relative standard deviation was 1.37%.