老年2型糖尿病发生低血糖的危险因素分析

Risk Factors for Hypoglycemia in Elderly Patients with Type 2 Diabetes Mellitus

目的分析老年2型糖尿病患者发生低血糖的危险因素,为老年2型糖尿病患者低血糖的预防提供可靠依据。方法于2013-01/2015-12,在该阶段内深圳市沙井人民医院、西丽医院门诊收治的老年2型糖尿病患者中,抽取45例出现低血糖反应的糖尿病患者和50例未出现低血糖的糖尿病患者。对这两组患者的临床资料进行回顾性的总结分析,对可能引起低血糖的相关因素进行病例对照研究,并探讨相应的预防措施。结果经单因素分析和多因素Logistics线性回归分析后得出,BMI指数过低、给予降糖药物前进食量过少、降糖药物应用不合理、空腹状态运动、擅自服用降血糖保健药物是导致老年2型糖尿病患者低血糖反应的危险因素。结论老年2型糖尿病患者发生低血糖反应的原因主要为BMI指数过低、进给予降糖药物前食量过少、降糖药物应用不合理、空腹状态运动、擅自服用降血糖保健药物,临床上应根据2型糖尿病患者发生低血糖反应的危险因素实施有针对性的预防措施,以减少低血糖的发生。

Objective To analyze the risk factors of hypoglycemia in elderly patients with type 2 diabetes, and to provide reliable evidences for disease prevention. Methods from January 2013 to December 2015, in elderly patients with type 2 diabetes in the stage, 45 patients with hypoglycemia and 50 without were selected with type 2 diabetes in Shajing Peopleg Hospital and Xili Hospital. The clinical data of the two groups were analyzed ret- rospectively, factors potentially related to hypoglycemia were studied, and the corresponding preventive meas- ures were discussed. Results According to single factor analysis and multivariate logistic linear regression analysis, low BMI index, insufficient food intake before administration of hypoglycemic agents, irrational use of hypoglycemic agents, activities on an empty stomach, and use of hypoglycemie agents without doctors＇ advice were the risk factors for hypoglycemic responses in elderly patients with type 2 diabetes. Conclusion In elderly patients with type 2 diabetes, the main causes of hypoglycemia included low BMI index, insufficient food intake before administration of hypoglycemic agents, irrational use of hypoglycemic agents, activities on an empty stomach, and use of hypoglycemic agents without doctors＇ advice. In clinical practice, measures against risks factors should be taken in elderly patients with type 2 diabetes to reduce hypoglycemic responses.