妊娠期反刍动物肝脏脂类代谢及相关疾病

Liver Lipid Metabolism and Its Associated Diseases of Ruminants during Pregnancy Period

妊娠期反刍动物的营养需求相较于未怀孕期大量增加。由于饲养管理不当,导致妊娠期反刍动物的营养摄入低于营养需要,当妊娠晚期反刍动物处于能量负平衡状态时,会发生体脂动员,过量的非酯化脂肪酸进入肝脏,造成肝脏脂类代谢紊乱,最终导致发生脂肪肝、酮病等疾病。

Compared to the non-pregnancy period, the ruminants have largely increased nutritional requirement during pregnancy period. The inappropriate measures of rearing and management always result in the nutritional deficiency of ruminants during pregnancy period. When ruminants are in a state of negative energy balance in late pregnancy period, lipid mobilization occurs, which leads to the transfer of excessive non-esterification fatty acids into liver and causes lipid metabolism disorders of liver, and subsequently results in fatty liver and ketosis.