血小板在静脉血栓形成及诊断中的作用研究进展

Research progress on role of platelets in development and diagnosis of venous thrombosis

静脉血栓是常见的血栓性疾病,容易发展为致死性肺栓塞,现有的治疗手段有限。尽管抗凝药物广泛应用,但是该病容易复发。近年来血小板在静脉血栓的形成及诊断方面已有诸多进展,抗血小板药物可能在静脉血栓的防治方面有一定的作用。这些新进展为我们以血小板为突破口找到更有效的治疗方法提供了新的思路。该文对近年来血小板在静脉血栓的形成和在诊断中的进展进行综述,探讨抗血小板策略在静脉血栓症方面的可能应用,为后续研究提供参考。

Venous thromboembolism,which is a common thrombotic disease,is prone to become a fatal pulmonary embolism due to the lack of existing treatments.Although the anticoagulant drugs are widely used,the disease relapses easily.In recent years,there are much progress in the formation of venous thrombosis and diagnosis,and antiplatelet agents may play a certain role in the prevention of venous thrombosis.These new developments provide a new train of thought that platelets play as a breakthrough to find more effective treatments.This article summarizes the progress in the diagnosis of venous thrombosis on platelets in recent years,which discusses whether antiplatelet strategies could be applied in venous thrombosis so as to provide reference for further research.