噬血细胞综合征研究进展

Progress in hemophagocytic syndrome

噬血细胞综合征（HPS）是由多种潜在病变引起淋巴细胞和组织细胞过度增生,产生细胞因子风暴所导致危及生命的炎症反应状态.HPS病因和临床表现错综复杂,且缺少特异性的症状,因而早期诊断困难,容易误诊和漏诊.文章对HPS的病因、临床表现、诊断及治疗作一综述.

Hemophagocytic syndrome is caused by a variety of potential lesions, resulting in excessive proliferation of lymphocytes and tissue cells, and a life-threatening inflammatory response caused by cytokine storms. Given that the etiology and clinical manifestations of the disease are complex and the specific symptoms are rare, so early diagnosis often occurs misdiagnosis and missed diagnosis. This article reviews the etiology, clinical manifestations, diagnosis and treatment of hemophagocytic syndrome.