内镜保胆取石术后结石复发分析:720例保胆患者随访资料

Gallstone recurrence after minimally-invasive cholecystolithotomy with gallbladder reservation: a follow-up of 720 cases

目的:讨论保胆取石术后结石复发的危险因素,为降低胆结石复发率提供理论依据。方法:选择720例行保胆取石术的胆囊结石患者,术后随访满一年。术后结石复发的患者为病例组,无结石复发的患者为对照组。通过收集患者病例数据、胆囊超声检查结果、患者调查问卷获取研究资料。统计学分析患者胆结石复发的相关因素,包括性别、年龄、BMI、油腻饮食、胆囊排空功能、家族史等。所选病例的信息均完整。结果:胆囊结石复发的主要危险因素是胆结石病家族史、胆囊排空功能。结论:胆结石复发仍是内镜微创保胆取石术后的主要问题。胆囊排空功能、胆结石家族史是胆囊结石复发的危险因素,建议此类患者应慎重考虑行保胆取石术。

Objective：To discuss the risk factors of cholecystolithiasis recurrence after cholecystolithotomy with gallbladder reservation;To provide a theoretical basis for reducing the recurrence rate of gallstone.Methods：The 720 patients who were followed up for at least one year after minimally-invasive operation with gallbladder reservation because of cholecystolithiasis were selected.In this population,the patients with recurrence after surgery were the case group,those patients without recurrence after surgery were the control group.Through collection of general data of selected cases,relevant information of ultrasound examinations of gallbladder and questionnaires were obtained.Relevant factors of gallstone recurrence were observed through statistic analysis.Main factors were as follows：gender,age,BMI,greasy diet,gallbladder emptying function,family history,etc.The information of selected cases was complete.Results：The main risk factors of cholecystolithiasis recurrence were family history of gallstone disease and emptying function of gallbladder.Conclusions：Gallstone recurrence is the major problem after minimally-invasive cholecystolithotomy with gallbladder reservation.The future indications in this surgery should take into account the risk factors of cholecystolithiasis recurrence,including the family history of cholecystolithiasis and emptying function of gallbladder.