高频超声联合超声造影在年轻乳腺癌诊断中的应用研究

Application of high-frequency contrast-enhanced ultrasonography in the diagnosis of breast cancer in young females

目的探讨高频超声联合超声造影在年轻乳腺癌诊断中的应用价值。方法选择103例女性乳腺癌患者(共103个病灶)为研究对象,依据患者年龄分为两组,对照组62例(年龄﹥35岁),研究组41例(年龄≤35岁)。所有患者均接受高频超声联合超声造影检查,比较分析两组患者的超声图像特征。结果研究组病灶的回声晕发生率和后方回声衰减率低于对照组,内部回声不均匀发生率高于对照组,差异均有统计学意义(P﹤0.05);研究组病灶造影前及造影后的横径均大于对照组,造影前纵横比、造影后横径差值均小于对照组,差异有统计学意义(P﹤0.01);研究组造影剂滞留率低于对照组,病灶快进快退率高于对照组,差异均有统计学意义(P﹤0.01)。结论高频超声联合超声造影在年轻乳腺癌诊断中具有重要价值,值得临床推广。

Objective To investigate the application of high-frequency contrast-enhanced ultrasonography （HF-CEUS） in the diagnosis of breast cancer in young females. Method 103 female breast cancer patients （a total of 103 le-sions） were included in the study, and were stratified as two groups, with 62 cases in control group （age〉35） and 41 cases in study group （age≤35）. All patients received HFCEUS, and the ultrasonic characteristics of both groups were analyzed. Result The rate of acoustic halo and posterior attenuation of the lesion in study group were lower than those of control group （P〈0.05）; the transverse diameter before and after angiography in study group were larger than that of control group, but aspect ratio before angiography and the difference of transverse diameter after angiography were less obvious than control group （P〈0.01）;the retention rate of contrast agent was lower, but the pattern of＆quot;quick in and quick out＆quot;was more in study group compared with control group （P〈0.01）. Conclusion HFCEUS is essentially useful in the diag-nosis of breast cancer in young females.