摘要
目前,随着多种细菌鉴定分型及其同源性分析方法的应用,临床实验室在流行菌株分析、流行病学研究及院内感控工作等方面有了很大进展。此文着重对目前常用方法学如脉冲场凝胶电泳、多位点序列分析、基质辅助激光解吸电离飞行时间质谱及规律成簇的间隔短回文重复序列进行概述。
At present ,with the application of bacterial typing and homology analysis methods, it has made great progress in epidemic strain analysis, epidemiology research and nosocomial infection control work in clinical laboratory. The article gives an overview of current common methods,such as pulsed-field gel electrophoresis, muhilocus sequence typing, matrix-assisted laser desorption-ionization time of flight mass spectrometry and clustered regularly interspaced short palindromic repeats.
出处
《国际流行病学传染病学杂志》
CAS
2017年第3期199-201,共3页
International Journal of Epidemiology and Infectious Disease
基金
天津市应用基础与前沿技术研究计划(15JCYBJC26300)
关键词
细菌分型技术
脉冲场凝胶电泳
多位点序列分析
基质辅助激光解吸电离飞行时间质谱
规律成簇的间隔的短回文重复序列
Bacterial typing technigues
Pulsed-field gel electrophoresis
Multilocus sequence typing
Matrix- assisted laser desorption-ionization time of flight mass spectrometry
Clustered regularly interspaced short palindromic repeats