NT-pro-BNP与LBP的表达对感染性心内膜炎的诊断意义及研究方案

Significance of the Expression of N Terminal Pro-brain Natriuretic Peptide and Lipopolysaccharidebinding Protein in the Diagnosis of Infective Endocarditis and the Study Protocol

近年,感染性心内膜炎发病率有升高趋势,具有死亡率高、诊断困难等特征。对NT-pro-BNP与LBP的研究旨在监测N末端脑钠肽前体(NT-pro-BNP)及脂多糖结合蛋白(LBP)在IE中的表达,探讨其能否作为诊断依据为IE诊断提供依据,期望早期确诊疾病,早期有效的控制病情,改善其预后。

In recent years, the incidence of infective endocarditis by high mortality and difficult diagnosis. The study on N terminal lipopolysaccharide binding protein （LBP） is to monitor the exp （ IE ） has been increasing, which is characterized pro brain natriuretic peptide （ NT-pro-BNP ） and ression of NT-pro-BNP and LBP in IE. This paper attempts to test the possibility of using the monitoring result as a basis for the early diagnosis of IE, and thus to make effective control of the disease and improve prognosis