纳洛酮治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床分析

Clinical Analysis of Naloxone in the Treatment of Chronic Obstructive Pulmonary Disease Complicated With Type Ⅱ Respiratory Failure

目的探究慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭治疗纳洛酮的应用效果。方法选择我院2013年3月—2017年3月收治的40例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者作为研究对象,所有患者均给予纳洛酮治疗,分析患者治疗后血气分析情况及治疗效果。结果 40例患者治疗后BR、HR、PaO_2、PaCO_2血气分析指标均得到不同程度改善,治疗总有效率为92.50%,并发症发生率为5.00%。结论纳洛酮具有良好的兴奋呼吸系统神经中枢作用,有效改善慢性阻塞性肺疾病合并呼吸衰竭患者的呼吸功能,给药简单、安全性和稳定性高。

Objective To study the effect of chronic obstructive pulmonary disease and type respiratory failure in the treatment of naloxone. Methods 40 cases patients with chronic obstructive pulmonary disease and type E3 respiratory failure were enrolled in our hospital from March 2013 to March 2017. All patients were treated with naloxone and analyzed the blood gas analysis and treatment after of treatment effect. Results The blood gas analysis indexes ofBR, HR, PaO2 and PaCO2 were improved in 40 patients. The total effective rate was 92.50% and the complication rate was 5.00%. Conclusion Naloxone has a good effect on the nerve center of excitatory respiratory system, which can effectively improve the respiratory function of patients with chronic obstructive pulmonary disease and respiratory failure. Safety and stability.