多囊卵巢综合征患者不同中医证型体质分布差异分析

Constitution Distribution Characteristics of Polycystic Ovary Syndrome Between Different TCM Types

目的:分析不同证型间PCOS患者体质分布情况,探讨中医证型体质的分布差异,从中医体质角度为PCOS中医辨证论治和防治提供临床依据。方法:收集2012年12月—2015年12月黑龙江中医药大学附属第一医院妇科门诊PCOS患者共460例,分为脾虚痰湿型组(139例)、痰瘀互结型组(116例)、肾虚肝郁型组(139例)、肾虚血瘀型组(66例);脾虚痰湿及痰瘀互结型组属于痰湿型组(255例),肾虚肝郁及肾虚血瘀型属于非痰湿型组(205例)。结果:(1)痰湿质、气虚质、气郁质在痰湿型与非痰湿型间分布具有明显差异(P<0.05),其余体质类型在2种证型间分布无明显差异(P>0.05);(2)痰湿质、气郁质在脾虚痰湿、痰瘀互结、肾虚肝郁、肾虚血瘀4种证型间分布具有明显差异(P<0.05),其余体质类型在四种中医证型间分布无明显差异(P>0.05;痰湿质分布在脾虚痰湿型和肾虚肝郁型间χ~2=6.31,P<0.05有统计学意义,痰瘀互结型和肾虚肝郁型间χ~2=4.89,P<0.05有统计学意义;气郁质分布在脾虚痰湿型和肾虚肝郁型间χ~2=5.86,P<0.05有统计学意义;痰瘀互结型与肾虚肝郁型间χ~2=4.7,P<0.05有统计学意义。结论:不同证型的PCOS患者中医体质分布存在差异,中医体质可能是导致PCOS证型差异的重要因素,对于发生PCOS的高危人群,通过中医辨体质,及早进行调整,可以预防PCOS的发生、发展。

Objective：To analyze the relativity between the nine different constitutions and the TCM syndromes of P- COS and provide new evidence for syndrome differentiation and treatment as well as the prevention of PCOS. Methods ： A total of 460 PCOS patients were divided into different groups according to syndrome differentiation of TCM. Results ： （ 1 ） Frequency of phlegm - damness constitution, qi - deficiency constitution and qi - depression constitution was significantly different in phlegm - damness syndrome and non phlegm - damness syndrome （ P 〈 0. 05 ）. （ 2 ） Frequency of phlegm - damness constitution and qi - depression constitution was different in four groups （ P 〈 0. 05 ）. Frequency of phlegm - damness constitution was significantly higher in spleen - deficiency and phlegm - dampness syndrome type , phlegm and blood stasis syndrome type than kidney- deficiency and qi -depression type,while the frequency of qi -depression con- stitution was significantly higher in latter than in the former. Conclusion：The distribution of constitution exists difference in TCM types, which may be the important factors for the difference of TCM types of PCOS. It suggests a new way to pre- vent and treat PCOS with adjusting constitutions.