滇东黔西晚二叠纪煤区肺癌患者临床流行病学特征分析

Analysis on clinical epidemiology feature of lung cancer patients in late permian coal-accumulating area in eastern Yunnan and western Guizhou

[目的]分析昆明医科大学第三附属医院2013-2015年收治的滇东黔西晚二叠纪聚煤区(主要包括宣威、富源和贵州盘县三个地区)原发性支气管肺癌患者的临床流行病学特征及病理类型分布特点。[方法]回顾性分析该院2013-2015年收治的首诊原发性支气管肺癌病例,按居住地不同对性别、年龄、病理类型、临床分期等临床资料进行对比分析;按病理类型对性别和年龄等临床资料进行对比分析。[结果]收集肺癌病例共6996例,男女比例为2.13∶1,三县合并与其他地区间女性患者所占比例差异有统计学意义(χ~2=80.5129,P<0.001);三县合并与其他地区间≤40岁患者比例差异有统计学意义(χ~2=19.9635,P<0.001);病理类型在富源、宣威、盘县3个地区和其它地区有统计学差异(χ~2=264.5905,P<0.001),三县合并与其他地区间I期患者比例差异有统计学意义(χ~2=245.4310,P<0.001)。[结论]来自滇东黔西晚二叠纪聚煤区的肺癌患者与其他地区的肺癌患者在性别构成、年龄分布、肺癌病理类型分布及肺癌临床分期分布方面差异均有统计学意义,有必要在该地区进行进一步的流行病学研究。

Objective It analyzes clinical epidemiology and pathology type distribution character of primary t）ronchogenic lung cancer patients whom received and cured in the third affiliated hospital of Kunming Medical University, were in late permian coal - accumulating area in eastern Yunnan and western Guizhou, China （included Xuanwei, Fuyuan and Pan county） . Methods Retrospectively analyzed the diagnosed primary bronchogenic lung cancer patients cases from 2013 to 2015 in this hospital. Contrastively analyzed the data of gender, age, pathology type and clinical stage according to different residence place, Contrastively analyzed the clinical data of gender, age according to pathology type. Results 6996 cases were colleeted, male female ratio was 2. 13 ： 1. There was statistical significance in proportion of the female lung cancer patients between three counties combination and other areas （X^2 = 80. 5129 P 〈 0. 001 ）, as well the patients ≤40 （X^2 = 19. 9635 P 〈 0. 001 ）, as well pathology type （X^2 = 264. 5905 P 〈0. 001 ）, and as well the stage I patients （X^2 =245. 4310 P 〈0. 001 ） . Conclusions There was sta- tistical significance in dirt%fence of gender, ages, pathology types distribution, in clinical stage distribution of lung cancer patients who are in late permian coal - accumulating area between eastern Yunnan and western Guizhou and other area. It is necessary that further cpidemiology research is needed in these areas.