楚雄州育龄期妇女乙肝血清学检测结果分析

Analysis on hepatitis B serology testing result of childbearing period women in Chuxiong

[目的]了解楚雄州现阶段育龄期妇女乙型病毒性肝炎的感染现状,为预防乙肝的垂直传播提供参考。[方法]在楚雄州10县(市)随机抽取15岁以上育龄期妇女978人,采集静脉血5 ml,统一检测表面抗原(HBsAg)、抗乙肝病毒表面抗原抗体(抗-HBs)、抗乙肝病毒c抗原抗体(抗-HBc);对育龄期妇女进行HBsAg流行状况分析。[结果]楚雄州育龄期妇女HBsAg阳性率为3.99%,抗-HBs阳性率为39.67%,抗-HBc阳性率为6.95%;少数民族与汉族育龄期妇女HBsAg阳性率之间的差异有统计学意义(P<0.05);在医院出生和在家出生的育龄期妇女HBsAg阳性率有统计学差异(P<0.05)。[结论]楚雄州少数民族育龄期妇女HBsAg阳性率高于全省同年龄段人群,控制HBV传播和阻断母婴HBV感染的任务还很艰巨,应加强和扩大乙肝疫苗接种的宣传,促进重点人群、高危人群接种乙肝疫苗。

Objective To understand current infectious status of Hepatitis B surface antigen （HBsAg） and anti hepatitis B virus surface antigen （anti -HBs） antibody, anti hepatitis B virus C antigen antibody （anti -HBc） among childbearing period women in Chuxiong prefecture, so as to provide reference for the prevention of vertical transmission of hepatitis B. Methods It randomly selected 978 childbearing period women whose age were over 15 years old fron 10 counties （cities） in Chuxiong. Collected 5ml venous blood from the respondents, detected HBsAg, anti -HBs and anti HBc. Analyzed HBsAg, anti -HBs and anti -HBc epidemic situation for childbearing period women. Results HBsAg positive rate of childbearing period women was 3.99% , positive rate of anti - HBs was 39. 67% , positive rate of anti - HBc was 6. 95%. There were statistically significant differences in HBsAg between minority and the Han nationality （ P 〈 0.05 ） . There were statistically significant differences in There were statistically significant differences between the situation of born in hospital and at home （ P 〈 0.05 ） . Conclu- sions HBsAg positive rate of minority childbearing period women was higher than the same age groups. The task of controlling HBV spread and blocking mother - infant HBV infection is very arduous. We should strengthen and expand the publicity of the hepatitis B vaccination, promote hepatitis B vaccination of key and high risk population.