摘要
目的:研究强直性脊柱炎中医辨证分型与风湿活动指标两者之间的相关性。方法:将强直性脊柱炎120例辨证分型为寒湿痹阻型、湿热壅滞型、瘀血阻络型、肾虚失养型,观察风湿活动指标血沉(ESR)、C反应蛋白(CRP)的变化,同时进行脊柱功能指标ASDAI和BASFI、Schober试验、枕壁距、扩胸度、指地距指标等观察;分析ESR、CRP水平及脊柱功能指标与辨证分型之间的关系。结果:湿热壅滞型、寒湿痹阻型ESR、CRP水平明显高于肾虚失养型、瘀血阻络型(P<0.01);而湿热壅滞型ESR、CRP水平又高于寒湿痹阻型(P<0.05);肾虚失养型、瘀血阻络型血清ESR、CRP水平无显著性差异(P>0.05)。湿热壅滞型、寒湿痹阻型功能指标如BASDAI和BASFI、Schober试验、枕壁距、扩胸度、指地距指标等显著高于肾虚失养型、瘀血阻络型(P<0.01),而湿热壅滞型又高于寒湿痹阻型(P<0.05)。结论:强直性脊柱炎活动期多见于湿热壅滞型、寒湿痹阻型,而静止期多以瘀血阻络型、肾虚失养型为主。
Objective:To study the correlation between differentiation of symptoms and signs for classification of syndrome with rheumatism activity index of ankylosing spondylitis.Methods:120 patients were randomly divided into four types:cold-dampness obstruction type,blood stasis blocked collaterals type,dampness-heat obstruction type,kidney deficiency type.The erythrocyte sedimentation rate (ESR),C reaction protein (CRP) were detected,spinal function such as ASDAI,BASFI,etc were observed and analyze the correlation between them.Results:ESR and CRP levels of cold-dampness obstruction type and dampness-heat obstruction type were high than those of blood stasis blocked collaterals type and kidney deficiency type,ESR and CRP levels of dampness-heat obstruction type were higher than those of cold-dampness obstruction type (P 〈 0.05).Spinal function indexes BASFI,pillow away from the wall,BASDAI,chest degrees,Schober test,refers to the distance in cold-dampness obstruction type,dampness-heat obstruction type were worse than those in blood stasis blocked collaterals type and kidney deficiency type,those in dampness-heat obstruction type were the worst (P 〈 0.05).Conclusion:The active stage of ankylosing spondylitis mainly showed dampness-heat obstruction type and cold-dampness obstruction type;blood stasis blocked collaterals type and kidney deficiency type were the common-seen in stationary phase.
出处
《中国中医药科技》
CAS
2017年第3期261-262,265,共3页
Chinese Journal of Traditional Medical Science and Technology
基金
中国人民解放军第117医院资助项目(2010YG029)