期刊文献+

妊娠合并自身免疫性疾病的抗凝治疗 被引量:8

Anticoagulation therapy for pregnancy complicated with autoimmune diseases
原文传递
导出
摘要 妊娠合并自身免疫性疾病患者因病理生理性的血栓形成倾向大大增加,常导致严重的母胎并发症。低分子肝素和阿司匹林等抗凝药物作为妊娠期安全用药,在改善此类患者的母胎结局中发挥着重要作用。因此,规范抗凝治疗有助于改善母胎不良结局。 The physiological and pathological changes of thrombophilia in pregnant women with autoimmune diseases often lead to severe pregnancy complications and adverse pregnancy outcomes.Low molecular weight heparin and aspirin,as the safe pregnancy medication,play an important role in improving the outcomes of these patients.Standardized treatment of anticoagulation helps to improve the maternal and fetal adverse outcomes.
作者 汪丽萍 钟梅
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2017年第7期684-688,共5页 Chinese Journal of Practical Gynecology and Obstetrics
关键词 自身免疫性疾病 妊娠 低分子肝素 阿司匹林 华法林 autoimmune diseases pregnancy low molecular weight heparin aspirin warfarin
  • 相关文献

参考文献5

二级参考文献95

  • 1李萍,朱付凡.抗磷脂抗体对妊娠的影响[J].中国优生与遗传杂志,2007,15(3):115-117. 被引量:6
  • 2王艳玲,吴华香.抗磷脂综合征与妊娠丢失的研究进展[J].中国妇幼健康研究,2007,18(1):44-46. 被引量:8
  • 3Ruiz-Irastorza G, Ramos-Casals M, Brito-Zeron P, et al. Clinical efficacy and side effects of antimalarials in systemic lupus ery- thematosus: a systematic review[J]. Ann Rheum Dis, 2010, 69: 20-28.
  • 4Willis R, Seif AM, McGwin G Jr, et al. Effect of hydroxych- loroquine treatment on pro-inflammatory cytokines and disease activity in SLE patients: data from LUMINA (LXXV), a multi- ethnic US cohort[J]. Lupus, 2012, 21 : 830-835.
  • 5Akhavan PS, Su J, Lou W, et al. The early protective effect of hydroxychloroquine on the risk of cumulative damage in patients with systemic lupus erythematosus [J]. J Rheumatol, 2013, 40: 831-841.
  • 6Shinjo SK, Bonfa E, Wojdyla D, et al. Antimalarial treatment may have a time-dependent effect on lupus survival: data from a multinational Latin American inception cohort [J]. Arthritis Rheum,2010, 62: 855-862.
  • 7Clowse ME, Magder L, Witter F, et al. Hydroxychloroquine in lupus pregnancy[J]. Arthritis Rheum, 2006, 54: 3640-3647.
  • 8Suarez-Almazor ME, Belseck E, Shea B, et al. Antimalarials for treating rheumatoid arthritis (review)[J/CD]. Cochrane Database Syst Rev, 2000(2) : CD000959.
  • 9Clegg DO, Dietz F, Duffy J, et al. Safety and efficacy of hydrox- ychloroquine as maintenance therapy for rheumatoid arthritis after combination therapy with methotrexate and hydroxychloroquine[J]. J Rheurnatol, 1997, 24: 1896-1902.
  • 10Carmiehael SJ, Beal J, Day RO, et al. Combination therapy with methotrexate and hydroxychloroquine for rheumatoid arthritis increases exposure to methotrexate[J]. J Rheumatol, 2002, 29: 2077-2083.

共引文献60

同被引文献84

引证文献8

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部