二硫化钼纳米片基纳米团簇的制备及其在近红外激光的热转换性能

Fabrication of MoS_2 Nanosheet-Based Nanocluster and Thermal Conversion Performance Under Near-Infrared Laser

探讨了γ-聚谷氨酸(γ-PGA)介导合成γ-PGA/二硫化钼(MoS_2)纳米团簇的可行性,分析了γ-PGA/MoS_2纳米团簇在近红外激光的热转换性能。将γ-PGA和合成MoS_2纳米片的前驱体四硫代钼酸铵同时溶解于蒸馏水中,通过水热法自下而上一步合成出了γ-PGA修饰的MoS_2纳米团簇,MoS_2纳米团簇的直径为(197.3±26.6)nm。团簇结构的形成可能与Mo^(4+)离子和γ-PGA链中羧基上氧原子的配位作用有关。在水热反应过程中,由于这种配位作用的存在,生成的MoS_2纳米片可能进一步以γ-PGA分子链中氧原子为中心形成团簇。该纳米团簇具有优异的胶体稳定性、光热转换性能(质量消光系数为11.23L·g^(-1)·cm^(-1))和细胞相容性,有望在肿瘤的光热治疗等领域得到应用。

The feasibility of γ-PGA/MoS2 nanocluster synthesized with the assistance ofγ-poly glutamic acid （γ- PGA） is discussed. Thermal conversion performance of γ-PGA/MoS2 nanocluster under near-infrared laser is analyzed. γ-PGA and （NH4）2 MoS4 which is the precursor of MoS2 nanosheet are dissolved into distilled water, and γ-PGA modified MoSz nanocluster is synthesized from bottom to top with hydrothermal method. The diameter of nanocluster is （197.3± 26.6） nm. NanocIuster configuration may he relevant to the coordination between Mo4＋ ion and oxygen atom belonging to the carboxyl group of γ-PGA. During the hydrothermal reaction process, generated MoSz nanosheets may form clusters due to the existence of coordination, and the oxygen atoms in γ-PGA molecular chain are the center. Nanoclusters show excellent colloidal stability, photothermal conversion performance （with mass extinction coefficient of 11.23 L·g ^-1 · cm^-1 ） and admirable cytocompatibility, and they are expected to be applied to the field of photothermal therapy for tumor.