微波促进下芳基硼酸合成芳香族硝基化合物的研究

Synthesis of Nitroarenes under Microwave

微波促进下,1,2-二氯乙烷为溶剂、反应温度120℃、反应时间1 min,系列芳基硼酸与五水合硝酸铋反应得到芳香族硝基化合物.相对于传统加热条件,微波促进反应具有:选择性高、时间短、副产物少等优点.此外,研究了自由基引发剂对该反应的影响,推测其可能是经过自由基转化.

The reaction of arylboronic acids with bismuth（Ⅲ） nitrate pentahydrate resulted in a series of nitroarenes when the reaction was carried out under microwave（120 ℃） for 1 min in 1,2-dichloroethane. Compared with traditional heating condition, the method of microwave condition for the preparation of nitroarenes was simple, efficient, time-saving, and of less by-products. In addition, possible free radical mechanism was proposed.