摘要
研究了一种微溶剂辅助高速球磨条件下的氧化Heck反应,用于高效制备2-乙烯基呋喃/噻吩化合物.这种钯催化氧化Heck偶联反应对丙烯酸酯和苯乙烯底物均具有较好的适用性,反应仅需45 min即可获得中等至较高收率的目标产物.
An efficient synthesis of 2-vinyl furans and thiophenes through oxidative Heck reaction has been explored under solvent-less high-speed ball-milling conditions. This Pd-catalyzed oxidative Heck reaction proceeded well with both acrylates and styrenes, which afford desired product in 45 min, with moderate to high yields.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2017年第6期1473-1478,共6页
Chinese Journal of Organic Chemistry
基金
国家重点基础研究发展计划(No.2014CB460608)
国家自然科学基金(Nos.21406201
21276237)资助项目~~
关键词
高速球磨
氧化Heck偶联
呋喃
噻吩
high-speed ball-milling
oxidative Heck coupling
furan
thiophene
