生物介质葡萄糖酸水溶液中5,5-(苯基亚甲基)双(2,2-二甲基二噁烷-4,6-二酮)衍生物的有效合成

Efficient Synthesis of 5,5-(Phenylmethylene)bis(2,2-dimethyl-1,3-dioxane-4,6-dione) Derivatives in Biobased Gluconic Acid Aqueous Solution

在生物介质葡萄糖酸水溶液中,以芳香醛和2,2-二甲基-1,3-二噁烷-4,6-二酮为原料,40℃合成了6种5,5-(苯基亚甲基)双(2,2-二甲基-1,3-二噁烷-4,6-二酮)衍生物.该反应具有收率高(81%~92%)、反应温和、操作简单及环境友好等优点.此外,葡萄糖酸溶液还可重复使用.

Six kinds of 5,5-（phenylmethylene）bis（2,2-dimethyl-1,3-dioxane-4,6-dione） derivatives were synthesized by the reaction of aromatic aldehydes and 2,2-dimethyl-1,3-dioxane-4,6-dione in biobased gluconic acid aqueous solution at 40 ℃. The reaction has the advantages of high yields（81%~92%）, mild conditions, simple operation and environmental friendliness. Furthermore, GAAS can be reused for several times.