浓缩生长因子对炎症期即刻种植临床效果影响的研究

Immediate implant placement in periodontally infected sites combined with concentrate growth factors: a clinical study

探讨浓缩生长因子(CGF)对炎症期即刻种植临床效果的影响。48例美学区牙周炎、根尖周炎行即刻种植患者共51颗患牙,观察组25颗患牙种植同期采用CGF联合Biooss引导骨再生(GBR);对照组26颗患牙GBR仅单独应用Bio-oss。于即刻种植当天、术后3个月、6个月测量种植体肩台下方0、4、8 mm处唇侧骨厚度;并采用疼痛视觉模拟评分(VAS)评价术后1周内患者疼痛程度。术后3个月种植体唇侧水平骨吸收量观察组低于对照组(P<0.05);术后前3天VAS评分观察组优于对照组(P<0.05)。CGF应用于炎症期即刻种植有较好的临床效果。

To investigate whether the use of concentrate growth factors have a favorable impact on clinical outcome of immediate implant in periodontally infected sites. 48 patients with 51 teeth with periodontitis and periapical peri-odontitis accepted immediate implantation in the maxillary esthetic zone. 25 implants（test group） were placed sim-ultaneously with guided bone regeneration （GBR） using CGF combined with Bio-oss, other 26 implants （ control group） were treated with Bio-oss alone. The facial bone thickness at 0, 4 and 8mm apical to the implant platform were measured immediately after, 3 months after and 6 months after surgery;pain visual analogue scale （ VAS） was used to assess the degreeof pain in the patient within 1 week after surgery. 3 months after surgery, the change of horizontal resorption in labial was less in test group （P 〈0. 05） . In the first three days postsurgery, the test group reported significantly less pain with respect to the control group（P 〈0. 05） . The application of CGF produced ben-eficial impacts on clinical outcome of immediate implant in periodontally infected sites.