成人中枢神经系统白血病临床分析

Clinical analysis of 52 patients suf fering from central nerve system leukemia

目的观察成人中枢神经系统白血病的高危险因素,以引起临床高度重视,并对中枢神经系统白血病进行早期诊断防治。方法对52例中枢神经系统白血病进行比较统计。结果急淋并发中枢神经系统白血病高于急性髓性白血病,高危险型白血病发生中枢神经系统白血病远高于标危型成人白血病,成人急性白血病初发时即合并中枢神经系统白血病较文献报道有所增加。结论成人中枢神经系统白血病与白血病类型、病程、初发时体内肿瘤负荷大小及对中枢神经系统白血病的防治方法有关,应引起临床高度重视,对中枢神经系统白血病早期诊断防治尤为重要。

Objective To observe the high risk factors of ad ult CNSL and pay more attention to its earlier diagnosis and treatment.Methods Statistical analysis was finished o n 52cases of CNSL carriers.Results Disease occurrence of acute clap CNSL patients was higher than that of acute marrow patients.Disease occu rrence for these patients with high r isk leukemia was higher than that of the standardized leukemia disease carriers.Discove ry of adult acute leukemia,i.e.,CNSL syndrome,had in-creased dramatically comparing with reports published in the media.Conclusions The factors of types of leukemia and c orre-lated with treatment and prevention methods of CNSL was crucial importan ce to the early diagnosis and treatme nt of CNSL and should pay great attention in the clinical practice.[