产后出血采用缩宫素加米索前列醇治疗的临床效果

Clinical Effect of Oxytocin Combined with Misoprostol in Treatment of Postpartum Hemorrhage

目的:观察产后出血采用缩宫素加米索前列醇治疗的临床效果。方法:选取收治的46例产后出血患者作为研究对象,利用随机数字表法分为观察组(23例)和对照组(23例)。观察组采用缩宫素加米索前列醇治疗,对照组单纯采用缩宫素进行治疗。结果:治疗后,与对照组相比,观察组患者的术后2 h、24 h出血量及宫缩恢复时间均明显缩短,具有显著性差异(t=6.74、8.23、13.59,均P<0.01)。观察组的不良反应发生率8.6%,对照组的不良反应发生率17.3%,两组比较差异无统计学意义(χ~2=2.10,P>0.05)。结论:采用缩宫素加米索前列醇治疗产后出血患者疗效显著,产后出血量少,宫缩恢复时间短,安全有效。

Objective To observe the clinical effect of oxytocin combined with misoprostol in treatment of postpartum hemor-rhage. Method 46 cases with postpartum hemorrhage were selected as the subjects,and they were divided into the observation group （23 cases） and the control group （23 cases） by the random number table. The control group were treated with oxytocin combined with misoprostol, and the observation group were treated with oxytocin alone. Results After treatment, compared with the control group,the bleeding volumeat at 2 h ,24 h after operation and contractions recovery time in the observation group of pa-tients were significantly shorter with significant differences （ t = 6 . 74,8. 23,13. 59,all P 〈0. 01）. The incidence of adverse reac-tions in the observation group was 8. 6 % ,and the incidence of adverse reactions in the control group was 17. 3 %. There was no significant difference between the two groups （x - 2 . 10,P 〉0. 05）. Conclusion The use of oxytocin combined with misoprostol in the treatment of postpartum hemorrhage patients with significant effect, less postpartum hemorrhage, short systolic recovery time,safe and effective.