新疆奎屯地区高尿酸血症的相关因素分析

Analysis of related factors of hyperuricemia in Kuitun District of Xinjiang

目的:调查新疆奎屯地区25~75岁人群高尿酸血症患病率及其相关影响因素。方法:在新疆奎屯地区调查了10 332例居民高尿酸血症患病情况并应用多因素Logistic回归模型分析高尿酸血症的影响因素。结果:高尿酸血症的患病率为14.4%,其中男性为17.8%,女性为10.9%;高尿酸血症伴发疾病中以高脂血症最为常见(83.2%),其次为超重和肥胖(77.3%)、高血压(39.2%)、糖尿病(13.2%);多因素Logistic回归模型显示:年龄(OR=1.03,95%CI:1.15~1.38)、男性(OR=1.36,95%CI:1.21~1.53)、肥胖(0R=1.85,95%CI:1.64~1.97)、饮酒(OR=1.44,95%CI:1.35~1.82)、经常吃肉(OR=1.51,95%CI:1.40~2.03)、高三酰甘油血症(0R=4.42,95%CI:3.94~5.01)、高胆固醇血症(OR=1.32,95%CI:1.01~1.55)、高血压(OR=1.24,95%CI:1.07~1.68)与高尿酸血症显著相关。结论:新疆地区高尿酸血症的危险因素包括饮酒、经常吃肉、年龄、男性、高血压、肥胖、高三酰甘油血症、高胆固醇血症;

Objective To investigate the prevalence of hyperuricemia and its risk factors in the adult population aged 25-75 years from the city of kuitun of xinjiang. Method 10 332 residents were recruited from the cross-sectional survey to determine the prevalence of hyperuricemia. Logistic regression model was used to investigate the association between uric acid levels and the various cardiovascular risk factors. Results The prevalence of hyperuricemia was 14. 4% and was higher for men( 17. 8%) than women( 10. 9%). The main concomitant disease of hyperuricemia were hyperlipemia( 83. 2%),then overweight and obesity(77. 3%),elevated blood pressure( 39. 2%),diabetes( 13. 2%). In a multivariate logistic regression model,age( OR = 1. 03,95% CI: 1. 15-1. 38),male gender( OR = 1. 36,95% CI: 1. 21-1. 53),obesity( OR = 1. 85,95% CI: 1. 64-1. 97),drinking( OR = 1. 44,95% CI: 1. 35-1. 82),often eating meat( OR = 1. 51,95% CI: 1. 40-2. 03),hypertriglyceridemia( OR =4. 42,95% CI: 3. 94-5. 01),hypercholesteremia( OR = 1. 32,95% CI: 1. 01-1. 55),elevated blood pressure( OR = 1. 24,95% CI: 1. 07-1. 68) were associated with increased risk of hyperuicemia. Conclusion Hypertriglycedemia,hypercholesteremia,male gender,elevated blood pressure,obesity and drinking are associated with increased risk of hyperuricemia.