高烯丙醇和高烯丙胺的电化学合成研究进展

Electrochemical Syntheses of Homoallylic Alcohols and Homoallylic Amines

电化学技术已经在有机合成得到广泛重视,本文简要概述了利用羰基和亚胺的电化学烯丙基化反应合成高烯丙醇和高烯丙胺的方法.该方法已取得了比较瞩目的进展,特别是在水相中的电化学烯丙基化反应,充分体现了绿色化学的特点.在提高电流效率和区域选择性、利用手性催化剂进行手性合成等方面还期待更多的关注和发展.

Electrochemical technique has been widely applied in the organic synthesis. This review focuses on the electrochemical syntheses ofhomoallylic alcohols and homoallylic amines from the allylation of carbonyl compounds and imines. This method has been developed impressively, especially in the field of electrochemical allylation with a green solvent of aqueous media. Im- provements in the efficiency of the electricity, regio-selectivity and chiral synthesis are expected.