期刊文献+

口服波生坦、西地那非及吸入伊洛前列素靶向治疗肺动脉高压的研究进展 被引量:3

下载PDF
导出
摘要 肺动脉高压(pulmonary arterial hypertension,PAH)是多种原因导致的肺血管床受累,肺循环血管阻力进一步增加,最终导致右心衰竭和死亡的一类严重疾病[1]。PAH主要指特发性、家族性、相关因素及因肺静脉或毛细血管病变导致的PAH。其中,相关因素导致的PAH主要包括胶原血管病、先天性体-肺分流性心脏病、门静脉高压、HIV感染、
出处 《北京医学》 CAS 2017年第7期658-660,共3页 Beijing Medical Journal
  • 相关文献

参考文献2

二级参考文献21

  • 1Humbert M,Morrell NW,Archer SL,et al.Cellular and molecular pathobiology of pulmonary arterial hypertension.J Am Coll Cardio,2004,43:13S-24S.
  • 2Tuder RM,Marecki JC,Richter A,et al.Pathology of pulmonary hypertension.Clin Chest Med,2007,28:23-42.
  • 3Rubin LJ.Current concepts:primary pulmonary hypertension.N Engl J Med,1997,336:111-117.
  • 4Tuder RM,Cool CD,Geraci MW,et al.Prostacyclin synthase expression is decreased inhngs from patients with severe pulmonary hypertension.Am J Respir Crit Care Med,1999,159:1925-1932.
  • 5Giaid A,Yanagisawa M,Langleben D,et al.Expression of endobethelin-1 in the lungs of patients with pulmonary hypertension.N EnglJ Med,1993,328:1732-1739.
  • 6Clapp LH,Finney P,Turcato S,et al.Differentialeffects of stable prostacyclin analogues on smooth muscle proliferation andcyclic AMP generation in human pulmonary artery.Am J RespirCell Mol Biul,2002,26:194-201.
  • 7Rybalkin SD,Rybaikina I,Beavo JA,et al.Cyclic nueleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation.Ciro Res,2002,90:151-157.
  • 8Schermuly RT,Inhulte C,Ghofrani HA,et al.Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension:amplification by different type phosphodiesterase inhibitors.Respir Res,2005,6:76.
  • 9Schermuly RT,Pullamsetti SS,Kwapiszewska G,et al.Phosphodiesterase 1 upregulation in pulmonary arterial hypertension:target for reverse-remodeling therapy.Circulation,2007,115:2331-2339.
  • 10Wharton J,Strange JW,Moller GM,et al.Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells.Am J Respir Crit Care Med,2005,172:105-113.

共引文献52

同被引文献35

引证文献3

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部