3种芳香植物香气物质的急性抗焦虑作用

Acute Anxiolytic-Like Effect of Volatile Composition from Three Species of Aromatic Plants

为了比较薰衣草(Lavandula angustifolia)、雪松(Juniperus virginiana L.)及苦水玫瑰(Rosa setate×Rosa rugosa)的香气物质经皮肤吸收后的急性抗焦虑效果,采用3种植物的精油进行志愿者皮肤涂抹实验。招募165名具有焦虑情绪的志愿者并随机分入基础油对照组和3个精油实验组,先以快速心算应激法使志愿者产生焦虑,再将4种油涂抹于志愿者背部的皮肤至吸收,比较志愿者血压及心率变异性相关生理指标的变化。结果显示雪松精油组(P=0.005)与薰衣草精油组(P=0.011)的低频高频比值的变化量均显著高于对照组,而苦水玫瑰组的各项指标相比对照组没有出现显著变化,结论认为薰衣草及维吉尼亚雪松的香气物质的急性抗焦虑效果优于苦水玫瑰,在康复花园植物配置中,可适当提高薰衣草及维吉尼亚雪松的种植率以提高抗焦虑功效。

The study aimed to compare the acute antianxiety efficacy of the volatile composition from lavender （ Lavandula angusti f olia ） , cedar （ J uni perus virginiana L. ） and rose （Rosa Setate× Rosa Rugosa） absorbed through skin. We recruited 165 volunteers and assigned them randomly into control group or essential oil groups. The base oil and plant essential oils were applied to the skin after volunteers were made anxious by mental arithmetic test （MAT）. The difference of physical signs, such as blood pressure and heart rate variety, after MAT and after oil absorption were compared to reflect the oil＇s antianxiety efficacy. The results showed that cedar （P = 0. 005） and lavender （P =0. 011） demonstrated significant reductions of low-to-high frequency ratio compared to the control group, while indicators of rose showed no changes, which reflected that the acute anxiolytic-like effect of lavender and cedarwood are better than Ku-shui rose. Therefore, appropriate increase of the planting rate of lavender and Virginia cedar may improve the efficacyof anti-anxiety garden.