摘要
目的研究桂野桐Mallotus conspurcatus中的化学成分。方法采用各种色谱分离手段对桂野桐75%乙醇粗提物的醋酸乙酯萃取部分进行分离纯化。运用1H-NMR、13C-NMR、ESI-MS等波谱方法以及与文献数据对比,鉴定化合物结构。结果从桂野桐根中分离得到18个化合物,分别鉴定为1,5-二羟基-3-甲氧基-7-甲基蒽醌(1)、(-)-丁香脂素(2)、2,3-二羟基-5,7-二-甲氧基-2,8-二甲基-6-(3-甲基-2-丁基)-吡喃-4-酮(3)、2,3-二氢-5,7-二羟基-2,6,8-三甲基-吡喃-4-酮(4)、paeoveitol B(5)、pinellic acid(6)、反式对羟基肉桂酸(7)、反式对甲氧基肉桂酸(8)、反式对羟基肉桂酸乙酯(9)、对羟基苯甲酸(10)、3-甲氧基-4-羟基苯甲酸(11)、3,4-二羟基苯甲酸(12)、阿魏酸(13)、丁香酸(14)、丁香酸乙酯(15)、1-正十六酸甘油酯(16)、没食子酸(17)和没食子酸乙酯(18)。结论除化合物3、4和13外,其余均为首次从野桐属植物中分离得到。
Objective To investigate the chemical constituents of Mallotus conspurcatus. Methods The ethyl acetate part of 75% ethanol extracts from M. conspurcatus was separated through chromatographic techniques. The isolates were identified on the basis of ^1H-NMR, ^13C-NMR, and ESI-MS data. Results Eighteen known compounds were isolated. They were 1,5-dihydroxy-3-methoxy-7-methyl-anthraquinon(1),(-)-syringaresinol(2), 2,3-dihydro-5,7-dihydroxy-2,8-dimethyl-6-(3-methyl-2-butenyl)-4H-1-benzo-4-one(3), 2,3-dihydro-5,7-dihydroxy-2,6,8-tri-methyl-4H-1-benzopyran-4-one(4), paeoveitol B(5), pinellic acid(6), trans-phydroxycinnamic acid(7), trans-p-methoxycinnamic acid(8), trans-p-hydroxy-ethyl cinnamate(9), p-hydroxybenzoic acid(10), 3-methoxy-4-hydroxybenzoic acid(11), 3,4-dihydroxybenzoic acid(12), ferulic acid(13), syringic acid(14), syringic acid ethyl ester(15), hexadecanoic acid 2,3-dihydroxy-propyl ester(16), galic acid(17), and ethyl gallate(18). Conclusion Besides compounds 3, 4, and 13, the other compounds are isolated from the plants of Mallotus Lour. for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2017年第11期2172-2176,共5页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(21662004)
广西教育厅项目(2017KY0779)