强筋壮骨祛风合剂对老年原发性骨质疏松症的临床观察

Clinical observation on Qiangjin Zhuanggu Qufeng Mixture in elderly primary osteoporosis

目的观察中医滋补肝肾方药强筋壮骨祛风合剂治疗老年原发性骨质疏松症的临床疗效。方法采用随机对照方法,将100例老年原发性骨质疏松症患者随机分成对照组和治疗组,每组各50例;对照组给予基础钙、维生素D治疗,口服碳酸钙D3咀嚼片和骨化三醇胶丸,疗程为6个月;治疗组在对照组基础上加用强筋壮骨祛风合剂,疗程为6个月。观察治疗前后两组患者中医症候评分变化,比较骨痛评分,检测跟骨骨密度(BMD)。结果治疗组患者中医证候总有效率显著高于对照组(P<0.05),对照组和治疗组治疗后患者骨痛症状均有所减轻,且治疗组效果强于对照组;两组治疗后跟骨BMD均有所上升,与治疗前比较差异显著(P<0.05),治疗组与对照组治疗后差异不显著。结论与基础钙、维生素D治疗基础上加用强筋壮骨祛风合剂可以改善患者中医证候、减轻骨痛症状,对升高BMD也有一定疗效。

Objective To observe the clinical effect of Qiangjin Zhuanggu Qufeng Mixture on treating elderly primary osteoporosis, which had the effect of formula of nourishing the liver and kidney. Method A total of 100 elderly primary osteoporosis treated in Hangzhou Hospital of Traditional Chinese Medicine were selected and randomly divided into control group and treatment group, 50 cases in each group. The control group was treated with calcium preparations, vitamin D, calcium carbonate, Vitamin D3 Chewable Tablets and Calcitriol Soft Capsules; The treatment group was treated with Qiangjin Zhuanggu Qufeng Mixture on the basis of the control group. All patients were treated for six months. The change of the Chinese medicine symptoms scores was observed, and metastatic bone pain scores and calcaneus bone density was compared. Result The effective rate of traditional Chinese medicine symptoms in the treatment group was significantly better than that in the control group. The metastatic bone pain scores of both groups mitigated after treating, and the treatment group was better. The level of calcaneus bone density improved significantly, but that in two groups had no statistically difference after treating. Conclusions Calcium preparations, vitamin D, calcium carbonate, Vitamin D3 Chewable Tablets, and Calcitriol Soft Capsules combined with Qiangjin Zhuanggu Qufeng Mixture could improve traditional Chinese medicine symptoms and bone density, and mitigate metastatic bone pain.