以肠道菌群为靶点的运动性胃肠综合征干预研究进展

Effect of Intestinal Flora on the Improvement of Exercise-induced Gastrointestinal Syndrome

运动性胃肠综合症是由运动引起机体胃肠系统出现功能性紊乱的一种病症,具备发病率高、范围广、原因复杂等特点,严重影响运动员的日常训练及比赛,因此如何有效防治成为研究重点。随着人类元基因组计划的启动,大量研究表明肠道菌群在维持肠道健康方面有着十分重要的作用。相关学者以肠道菌群为靶点,研究运动性胃肠综合征的发病机制后发现保证运动员肠道菌群的多样性和丰度可有效改善其症状,成为防治运动性胃肠综合征的新方法。故本文采用文献资料等方法分析运动性胃肠综合症的发病类型、影响因素及发病机制,剖析以肠道菌群为介入点改善运动性胃肠综合征的作用机理,深入总结前人研究,为运动性胃肠综合症及其防治的相关研究提供理论依据。

Exercise-induced gastrointestinal syndrome is due to the functional disorder of gastroin- testinal system caused by exercise. It is characterized by high incidence rate, wide range and com- plicated causes. It seriously affects the athletes＇ daily training and competition. How to effectively control the syndrome has become a hot research topic. Following the research on human genome, a large number of studies have indicated that intestinal flora plays an important role in the mainte- nance of intestinal health. Some scholars used the intestinal flora as the target and studied the mechanism of exercise-induced gastrointestinal syndrome. They found that to ensure the diversity and abundance of athletes＇ intestinal flora can effectively improve the symptom. This has become a new method of preventing and curing exercise-induced gastrointestinal syndrome. The paper uses the method of literature study to discuss the types, influence factors and mechanism of the exer- cise-induced gastrointestinal syndrome and analyze the functional mechanism of using intestinal flora to improve exercise-induced gastrointestinal syndrome. By summarizing the achievements of the previous researches, the paper tries to provide theoretical basis for the researches on preventing exercise-induced gastrointestinal syndrome.