肝动脉栓塞化疗联合微波消融术治疗原发性肝癌的临床应用

Clinical Application of Transcatheter Arterial Chemoembolization Combined with Microwave Ablation in the Treatment of Primary Liver Cancer

目的观察肝动脉栓塞化疗联合微波消融术治疗原发性肝癌的临床应用。方法选取我院2013年12月至2016年6月收治的64例原发性肝癌患者,随机分为两组各32例。对照组采取常规肝动脉栓塞化疗,研究组采用肝动脉栓塞化疗联合微波消融术治疗。对比两组患者的治疗效果。结果研究组的治疗总有效率、并发症发生率、两年生存率和转移率均优于对照组,差异均有统计学意义(P<0.05);研究组的CD_3^+、NK细胞、TNF-α水平和生活质量评分均高于对照组,差异均有统计学意义(P<0.05)。结论肝动脉栓塞化疗联合微波消融术治疗原发性肝癌,疗效确切,安全可靠,值得推广。

Objective To observe the clinical application of transcatheter arterial chemoembolization combined with microwave ablation in the treatment of primary liver cancer. Methods 64 cases of patients with primary liver cancer admitted to our hospital from December 2013 to June 2016 were selected and randomly divided into two groups, with 32 cases in each group. The control group received conventional transcatheter arterial chemoembolization, while the study group received transcatheter arterial chemoembolization combined with microwave ablation. The treatment effect of patients were compared between two groups. Results The total effective rate of treatment, incidence of complications, 2-year survival rate and transfer rate of study group were better than those of control group, with statistical differences （P〈0.05）. The CD[, NK and TNF-ct levels and quality of life score of study group were higher than those of control group, with statistical differences （P 〈0.05）. Conclusions Transcatheter arterial chemoembolization combined with microwave ablation in the treatment of primary liver cancer has exact curative effect, and is safe and reliable, which is worthy of promotion.