乳腺癌肝转移研究进展

Research progress of liver metastasis in breast cancer

目的探讨乳腺癌肝转移的临床表现、发生机制、诊断及治疗。方法检索Pub Med及CNKI期刊全文数据库乳腺癌肝转移相关研究文献并作综述。结果有关乳腺癌肝转移的相关研究甚多,乳腺癌肝转移的诊断方法包括了CT、B超、磁共振、检验相关血清学指标、病理活检等,治疗方面包括了全身治疗及局部治疗。但转移机制尚未完全阐明,临床表现较为突出。结论虽然乳腺癌肝转移发病率相对较低,但严重影响了乳腺癌患者生活质量及预后,故需对其进一步深入研究、探讨其发生机制,为乳腺癌肝转移的诊断及治疗提供依据,达到更好的远期预后。

Objective To investigate the mechanism, manifestation, diagnosis and treatment of liver metastasis from breast cancer. Methods The literatures on liver metastasis of breast cancer in PubMed and CNKI ]ournal Full-text Database were reviewed. Results There are many related studies on the liver metastasis of breast cancer. The diagnosis methods of breast cancer with liver metastasis include CT, B-ultrasound, magnetic resonance imaging, inspection related serological index, pathological biopsy, etc. In the treatment, including systemic treatment and local treatment. However, the transfer mechanism has not been fully clarified, and the clinical manifestations are more prominent. Conclusions Although the liver metastasis of breast cancer incidence is relatively low, but seriously affected the quality of life of patients with breast cancer and prognosis, it is needed to further study and explore the mechanism, provide the basis for the diagnosis and treatment of liver metastasis of breast cancer, achieve long-term prognosis better.